Chlorinated withanolides from Withania somnifera
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چکیده
منابع مشابه
Cholinesterase inhibiting withanolides from Withania somnifera.
A total of two new (1, 2) and four known (3-6) withanolides were isolated from the whole plant of Withania somnifera. Their structures were elucidated on the basis of spectroscopic techniques and were characterized as 6alpha,7alpha-epoxy-3beta,5alpha,20beta-trihydroxy-1-oxowitha-24-enolide (1), 5beta,6beta-epoxy-4beta,17alpha,27-trihydroxy-1-oxowitha-2,24-dienolide (2), withaferin-A (3), 2,3-di...
متن کاملAntioxidant activity of glycowithanolides from Withania somnifera.
Antioxidant activity of active principles of Withania somnifera, consisting of equimolar concentrations of sitoindosides VII-X and withaferin A, was investigated for their effects on rat brain frontal cortical and striatal concentrations of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX). Results were compared with effects induced by deprenyl, an agent with well docu...
متن کاملTherapeutic Uses of Withania Somnifera (ashwagandha) with a Note on Withanolides and Its Pharmacological Actions
Withania somnifera is a medicinal plant extends over a large area, from the Atlantic ocean to South East Asia and from the Mediterranean region to South Africa. The medicinal plants are widely used by the traditional medical practitioners for curing various diseases in their day to day practice. In traditional systems of medicine, different parts (leaves, stem, flower, root, seeds, bark and eve...
متن کاملOf withania somnifera pdf
Gate the properties of ashwagandha in an attempt to authenticate its use as a.Asgand consists of the roots of Withania somnifera which has various therapeutic actions such as. Withania somnifera Dunal belongs to the family solanaceae.Withania somnifera is a medicinal plant extends over a large area, from the.
متن کاملDetermination of withanolides from the roots and herbal formulation of Withania somnifera by HPLC using DAD and ELSD detector
Roots of Withania somnifera are widely used in Indian herbal formulations. Withaferine A and withanolide A are two pharmacologically important withanolides present in the roots of the plant. HPLC method using DAD and ELSD detector was developed for simultaneous determination of withaferine A and withanolide A from the roots and herbal formulation of the plant. Coarse powder of root was extracte...
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ژورنال
عنوان ژورنال: Phytochemistry Letters
سال: 2011
ISSN: 1874-3900
DOI: 10.1016/j.phytol.2011.04.016